Annexin A1 is elevated in patients with COPD and affects lung fibroblast function
نویسندگان
چکیده
منابع مشابه
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function
Purpose Fibrosis in peripheral airways is responsible for airflow limitation in chronic obstructive pulmonary disease (COPD). Annexin A1 modulates several key biological events during inflammation. However, little is known about its role in airway fibrosis in COPD. We investigated whether levels of Annexin A1 were upregulated in patients with COPD, and whether it promoted airway fibrosis. Met...
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BACKGROUND Annexin-A1 (ANXA1) is a glucocorticoid-induced protein with multiple actions in the regulation of inflammatory cell activation. The anti-inflammatory protein ANXA1 and its N-formyl peptide receptor 2 (FPR2) have protective effects on organ fibrosis. However, the exact role of ANXA1 in asthma remains to be determined. The aim of this study was to identify the role of ANXA1 in bronchia...
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چکیده ندارد.
Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function
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ژورنال
عنوان ژورنال: International Journal of Chronic Obstructive Pulmonary Disease
سال: 2018
ISSN: 1178-2005
DOI: 10.2147/copd.s149766